Lattice Graph × Chemours

Lattice Graph is a computational materials-discovery platform built around a knowledge graph that spans millions of compositions. Every candidate material is validated by consensus across multiple independent machine-learning interatomic potentials — MACE, CHGNet, MatterSim, and ORB — before a result is considered credible, and that consensus is further anchored by density functional theory calculations. Phonon and thermodynamic stability must both be confirmed before a composition advances, which eliminates the false positives that plague single-model discovery workflows. The platform then runs targeted simulations on survivors, dramatically compressing the experimental shortlist. Alongside the discovery engine, Lattice Graph maintains a large atlas of labeled negative results — failed-experiment data that most organizations discard but that is essential for training reliable models and avoiding expensive re-runs of known dead ends. A freedom-to-operate and patent-whitespace screening capability covers more than 300,000 materials patents at the composition and claim level, letting a chemistry team know whether a candidate has a clear intellectual property path before synthesis resources are committed. The combination of multi-model consensus, DFT grounding, negative-data coverage, and integrated patent screening is not available from any other single platform.

Chemours occupies a pivotal and exposed position in the cooling-fluid market. The company launched Opteon two-phase immersion fluid precisely as 3M exited its roughly $12.5 billion PFAS and Novec engineered-fluid business at the end of 2025, capturing significant white space in a market that analysts track from approximately $2 billion today toward $11 billion as data-center liquid cooling becomes standard infrastructure. That is a strong near-term position, but it rests on a fluorinated chemistry that carries the same long-term regulatory and reputational risk that drove 3M out of the segment entirely. The next competitive wave — a PFAS-free two-phase immersion coolant that matches Opteon's thermal performance — is not a distant scenario; it is the predictable response of the market, and Chemours needs to either own it or be ready for it. Lattice Graph addresses both sides of that strategic question. On offense, the PFAS-free dielectric and process fluids portfolio represents computationally validated candidates for precisely the genus Chemours would need to develop or acquire to hold the immersion-cooling category beyond the current regulatory cycle. On defense, the integrated PFAS-treatment and fluoride-accounting capability speaks directly to Chemours's broader fluorochemical franchise: as regulators tighten disclosure and destruction requirements for PFAS-containing products, a rigorous fluoride mass-balance and destruction-routing tool becomes a compliance asset, not merely an R&D curiosity. Chemours also brings deep expertise in performance coatings, titanium technologies, and advanced materials, all of which intersect with the platform's knowledge graph in ways that extend beyond the cooling-fluid headline. The combination of a materials-discovery engine with freedom-to-operate screening means Chemours can evaluate new compositions for both technical merit and intellectual property exposure in the same workflow — a capability that matters for a company operating across as many regulated chemistry domains as Chemours does.

Chemours occupies a pivotal and exposed position in the cooling-fluid market. The company launched Opteon two-phase immersion fluid precisely as 3M exited its roughly $12.5 billion PFAS and Novec engineered-fluid business at the end of 2025, capturing significant white space in a market that analysts track from approximately $2 billion today toward $11 billion as data-center liquid cooling becomes standard infrastructure. That is a strong near-term position, but it rests on a fluorinated chemistry that carries the same long-term regulatory and reputational risk that drove 3M out of the segment entirely. The next competitive wave — a PFAS-free two-phase immersion coolant that matches Opteon's thermal performance — is not a distant scenario; it is the predictable response of the market, and Chemours needs to either own it or be ready for it. Lattice Graph addresses both sides of that strategic question. On offense, the PFAS-free dielectric and process fluids portfolio represents computationally validated candidates for precisely the genus Chemours would need to develop or acquire to hold the immersion-cooling category beyond the current regulatory cycle. On defense, the integrated PFAS-treatment and fluoride-accounting capability speaks directly to Chemours's broader fluorochemical franchise: as regulators tighten disclosure and destruction requirements for PFAS-containing products, a rigorous fluoride mass-balance and destruction-routing tool becomes a compliance asset, not merely an R&D curiosity. Chemours also brings deep expertise in performance coatings, titanium technologies, and advanced materials, all of which intersect with the platform's knowledge graph in ways that extend beyond the cooling-fluid headline. The combination of a materials-discovery engine with freedom-to-operate screening means Chemours can evaluate new compositions for both technical merit and intellectual property exposure in the same workflow — a capability that matters for a company operating across as many regulated chemistry domains as Chemours does.

The PFAS-free dielectric and process fluids portfolio is the primary match for Chemours and maps directly onto the Opteon franchise and its successor chemistry. This portfolio contains computationally validated compositions and system designs for immersion cooling, vapor cleaning, electronics-grade purification, and dielectric process use cases — each candidate confirmed by the platform's multi-model consensus workflow and DFT grounding. For Chemours, the strategic value is twofold: these materials can serve as the starting point for an internal PFAS-free two-phase coolant program, or they can inform competitive intelligence on what a credible Opteon challenger would look like. Either way, understanding this space before a competitor does is the more valuable position. The Integrated packaging, storage and PFAS-treatment systems portfolio is the defensive complement. Chemours's fluorochemical business means the company generates, handles, and in some cases destroys PFAS-containing materials at scale. The PFAS-destruction selector with triple-verified fluoride mass balance in this portfolio addresses the compliance infrastructure that regulators are increasingly requiring — not as a future obligation but as a present one in multiple jurisdictions. Pairing this capability with the offensive coolant program creates a coherent story for Chemours's fluorochemical franchise: building the next generation of products while demonstrating rigorous accountability for the current generation. The high-power thermal-interface materials portfolio is a secondary but meaningful adjacency. As the data-center cooling stack evolves, the boundary between bulk immersion fluid and chip-level thermal interface is where the next performance gains will be found. Chemours's position in advanced materials and coatings gives it a natural path into that space, and the platform's phonon-confirmed candidates in this portfolio provide a validated starting point for materials that sit at that interface.

The Lattice Graph platform gives chemistry and R&D teams a single environment for running the full discovery-to-decision workflow. Researchers can submit composition hypotheses to the multi-model validation pipeline — which runs MACE, CHGNet, MatterSim, and ORB in parallel and requires consensus on phonon and thermodynamic stability before flagging a candidate — and receive results ranked by confidence rather than by any single model's output. The negative-data atlas is searchable alongside positive results, so a team evaluating a new coolant candidate can immediately see what related chemistries failed in prior work and why, avoiding redundant experimental paths. Patent-whitespace screening is integrated directly into the candidate evaluation view, so a materials scientist does not need to hand off to a legal or IP team to get a preliminary read on whether a composition has a clear path. For Chemours's regulatory and compliance workflows, the fluoride mass-balance and PFAS-destruction routing tools surface the information needed to respond to evolving disclosure requirements in a format that can be shared with regulators and customers without additional translation. The platform is designed for teams that need to move between offensive discovery work and defensive compliance documentation within the same program cycle.

An engagement with Lattice Graph typically begins with a focused scoping session in which Chemours's R&D and strategy teams define the two or three compositional or process questions with the highest near-term leverage — for example, identifying the PFAS-free immersion-coolant candidates with the best thermal performance envelope and the clearest patent whitespace, or routing the existing fluorochemical portfolio through the PFAS-destruction selector to establish a fluoride mass-balance baseline. From that scoping session, Lattice Graph delivers a ranked candidate report within four to six weeks, including stability validations from the multi-model pipeline, targeted simulation results, and a freedom-to-operate summary for each surviving composition. Following the initial report, teams typically move into a structured discovery sprint in which the shortlisted candidates are advanced through more targeted simulations and the patent-whitespace screening is extended to cover adjacent claims and competitor filings. Deliverables across a full engagement include validated composition candidates, simulation data packages suitable for supporting synthesis decisions, and a patent-landscape summary. Pricing is scoped to the specific question set and data products required; engagements typically run in the range appropriate for a strategic R&D program, with data-access licensing available separately for teams that want ongoing access to the knowledge graph and patent API.